A ready-to-use kit for rapid
assessment of drug candidates' binding a1-acid
glycoprotein (AGP) plasma protein
A novel ready-to-use binding kit designed to assess the
binding of drugs to plasma binding protein and mimic the
physiological condition of the major plasma protein
a1-acid glycoprotein (AGP).
The affinity of a drug candidate to plasma proteins is a
true measurement of the free fraction of a drug candidate in
plasma.
Benefits
Fast, requiring only 2 minutes for
incubation.
Accurate. Measures the affinity of
the drug candidate to a1-acid
glycoprotein (AGP) a true measurement of the
free fraction in plasma, capable of producing
pharmacological effects.
Reliable with highly reproducible
results.
Ready-to-use format plated in 96-well
or ready-to-use tubes in strips of 8. Kit only
requires addition of test material, 2-minute
incubation, and quantification.
Flexible. Enables physiology based
modeling (e.g Simcyp) by providing affinity
input data. Format is adaptable to automation.
GENTAUR Germany
Marienbongard 20
GENTAUR Italy
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Schweiz Züri
Canada Montreal
US New York
日本